Effect of the extract combinations of Curcuma zedoaria and Aloe vera in retarding melanin synthesis in murine melanoma cells
نویسندگان
چکیده
The objective of the study was to determine the effect of role of combination of extracts of Curcuma zedoaria and Aloe vera in reducing melanin synthesis. Varying concentrations of the extracts of the plants were tested for melanogenesis and tyrosinase activity in murine melanoma cells. Extract combinations at a concentration of 1-5μl showed 50150% reduction in melanogenesis without altering the cell proliferation. Tyrosinase activity was very low in extract treated cells when compared to control.
منابع مشابه
Extract combinations of Curcuma zedoaria and Aloe vera inhibit melanin synthesis and dendrite formation in murine melanoma cells
The objective of the study was to determine the effect of role of combination of extracts of Curcuma zedoaria and Aloe vera in reducing melanin synthesis. Yarying concentrations of the extracts of the plan ts were tested for melanogenesis and tyrosinase activity in murine melanoma cells. Extract combinations at a concentrati on of 1-5μ1 showed 50J 50% reduction in melanogenesis without altering...
متن کاملAnti-melanogenic activity of Viola odorata different extracts on B16F10 murine melanoma cells
Objective(s): In previous studies, antioxidant activity of Viola odorata L. has been demonstrated. In this study, we have investigated the anti-melanogenic effect of extract and fractions of the plant in B16F10 cell line. Materials and Methods: Impact of different increasing concentrations of extract and fractions of V. odorata was evaluated on cell viability, cellular tyrosinase, melanin conte...
متن کاملEvaluation of antioxidant and anti-melanogenic activities of different extracts from aerial parts of Nepeta binaludensis Jamzad in murine melanoma B16F10 cells
Objective(s): Nepeta binaludensis Jamzad (Lamiaceae) has been used in folk medicine of Iran to cure various diseases. The plant is an endemic species to the country that has recently been identified in Razavi Khorasan province. To evaluate the antioxidant and anti-melanogenesis of N. binaludensis, in this study the inhibitory activity of different extracts of N. binaludensis in murine melanoma ...
متن کاملEffect of Curcuma zedoaria crude extract against tumor progression and immunomodulation
The aim of the present work was to study the effect of the crude extract of Curcuma zedoaria on peripheral blood cells and tumor progression in C57Bl/6J mice injected with B16F10 murine melanoma cells. The intraperitoneal therapy showed a significant increase in total white and red blood cell counts, a decrease in peritoneal cell number and tumor volume reduction, whereas the oral administratio...
متن کاملAnti-melanogenic activity of different extracts from aerial parts of Nepeta glomeruloasin on murine melanoma B16F10 cells
Nepeta glomerulosa Boiss. is a medicinal plant has been used in traditional medicine. The aim of this study was to evaluate the anti-melanogenesis inhibitory activity of MeOH, n-hexane, ethyl Acetate (EtAc), dichloromethane (CH2Cl2), n-butanol (BuOH) and H2O extracts isolated from N. glomerulosa in B16 melanoma cell line. The B16F10 cell line viability after treatment with increasing concentrat...
متن کامل